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Phrixotoxin 3 TFA Catalog No.:M17683-C InChi: InChI=1S/C23H18N2O2/c26-22(23(27)24-18-11-5-2-6-12-18)20-16-25(15-17-9-3-1-4-10-17)21-14-8-7-13-19(20)21/h1-14

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Description

InChi: InChI=1S/C23H18N2O2/c26-22(23(27)24-18-11-5-2-6-12-18)20-16-25(15-17-9-3-1-4-10-17)21-14-8-7-13-19(20)21/h1-14

Biorobin (Kaempferol 3-O-robinobioside) inhibits the in vitro proliferative response of human T-cells (IC50=25 mg/mL)

BMS-477118

Na/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9

Phrixotoxin 3 TFA Catalog No.:M17683-C InChi: InChI=1S/C23H18N2O2/c26-22(23(27)24-18-11-5-2-6-12-18)20-16-25(15-17-9-3-1-4-10-17)21-14-8-7-13-19(20)21/h1-14Phrixotoxin 3 TFA is a potent blocker of voltage gated sodium channels, with IC50s of 0. 6, 42, 72, 288, 610 nM for NaV1. 2, NaV1. 3, NaV1. 4, NaV1. 1 and NaV1. 5, respectively. Phrixotoxin 3 TFA modulates voltage gated sodium channels with properties similar to those of typical gating modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current. Product information Molecular

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