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while 14-fold higher concentrations are required in rat plasma (IC50 290 nM)
The molecular targets of CE and DBZ are the N-terminal fragment of presenilin 1 within the γ-secretase complex
InChi: InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23
19(6):6975-86
Roxindole hydrochloride lesteryl sulfate sodium while 14-fold higher concentrations areProduct information CAS Number: 108050 82 4 Molecular Weight: 382. 93 Formula: C23H27ClN2O Chemical Name: 3 [4 (4 phenyl 1,2,3,6 tetrahydropyridin 1 yl)butyl] 1H indol 5 ol hydrochloride Smiles: Cl. OC1C=C2C(=CC=1)NC=C2CCCCN1CC=C(CC1)C1C=CC=CC=1 InChiKey: ZCEPVNSWLLJECX UHFFFAOYSA N InChi: InChI=1S C23H26N2O. ClH c26 21 9 10 23 22(16 21)20(17 24 23)8 4 5 13 25 14 11 19(12 15 25)18 6 2 1 3 7 18; h1 3,6 7,9 11,16 17,24,26H,4 5,8,12 15H2; 1H Technical