SR1078 - CAS# 1246525-60-9 acapone Neuronal cultures treated with other

Neuronal cultures treated with other toxic stimuli such as staurosporine

CFTR(Inh)172

with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis

8E)-9-((E)-3-((((S)-3-benzhydryl-1-((S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidin-2-yl)-1

SR1078 - CAS# 1246525-60-9 acapone Neuronal cultures treated with otherSR 1078 is a selective agonist of ROR and ROR that stimulates ROR transcriptional activity in HEK293 cell reporter assays at concentrations as low as 2 M without effect at the related liver X receptors and farnesoid X receptors. SR1078 modulates the conformation of ROR in a biochemical assay and activates ROR and ROR driven transcription. SR1078 stimulates expression of endogenous ROR target genes in HepG2 cells that express both ROR and ROR. SR1078