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Flutamide - CAS# 13311-84-7 Catalog No.:M7030-2 with 50 % inhibition at

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Description

with 50 % inhibition at 10 μM

1014691-61-2

Arthritis Rheum

GF-109203X inhibited GSK-3 in vitro

Flutamide - CAS# 13311-84-7 Catalog No.:M7030-2 with 50 % inhibition atFlutamide, CAS No. 13311 84 7, also known as SCH13521, is a toluidine derivative and nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2 hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen dependent DNA and

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