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Chemical Name: 3-methyl-1-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)thiourea
InChi: InChI=1S/C58H82N8O14S2/c1-37-49(81-35-61-37)41-13-9-39(10-14-41)29-59-53(71)45-27-43(67)31-65(45)55(73)51(57(3
Chemical Name: (5R)-5-methyl-2-(propan-2-ylidene)cyclohexan-1-one
It binds to the Smo receptor (Kd = 12 nM) and inhibits binding of the Smo receptor agonist SAG-1
BMS 599626 dihydrochloride Catalog No.:M23416-C Chemical Name: 3-methyl-1-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)thioureaBMS 599626 dihydrochloride is a potent and selective inhibitor of EGFR and ErbB2 with IC50 values of 22 and 32 nM, respectively . The epidermal growth factor receptor (EGFR) is the cell surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation. Receptor tyrosine protein kinase erbB 2 (ErbB2) is a human epidermal growth factor receptor and plays a critical role in breast cancer. BMS 599626