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AMG 487 - CAS# 473719-41-4 Catalog No.:M10194-2 Chemical Name: 5H-Dicyclopenta(b

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Description

Chemical Name: 5H-Dicyclopenta(b

increasing the bioavailability of trifluiridine

Molecular Weight: 377

Smiles: O=C(NC1=CC=CC2=C1OC(=CC2=O)C1NN=NN=1)C1C=CC(=CC=1)OCCCCC1C=CC=CC=1

AMG 487 - CAS# 473719-41-4 Catalog No.:M10194-2 Chemical Name: 5H-Dicyclopenta(bAMG 487 is a potent and selective antagonist of chemokine (C X C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8. 2nM for I IP 10 and I ITAC, respectively. AMG 487 prevents the chemokines I IP 10 and I ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3 mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I IP 10, I ITAC and MIG, respectively. Product information CAS Number: 473719 41 4 Molecular Weight:

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